There are no known alternatives to platelet concentrates. Description of plasma products distributed by Canadian Blood Services. Canadian Blood Services Customer Letter # 2017-29: Important Information Regarding Changes to the Expiry Date of Irradiated Red Blood Cells.
Approximately 200 to 400 mL of plasma are obtained from each whole blood transfusion bag. FP, CSP, and AFFP anticoagulated with ACD-A can be stored up to five days; however, AFFP anticoagulated with sodium citrate) is collected in an open system and can be stored for only 24 hours (at 1–6°C) after thawing. Blood products may be returned to inventory only if the bag is intact, passes a visual inspection and has maintained an acceptable temperature (See CSTM Standard 5.8.7.1 for more information).3. Whole blood can be used immediately or stored at 4°C for future transfusion or separation into blood components.
COVID-19: FAQ for health professionals working with blood products, AFC-diploma program in transfusion medicine, Blood System Inventory Management Best Practices Guide, International Collaboration for Transfusion Medicine Guidelines (ICTMG), Testing and management of fetal and neonatal alloimmune thrombocytopenia, Use of cytomegalovirus (CMV) seronegative blood products, Molecular immunohematology at Canadian Blood Services: Red cell antigen genotyping, Paying it forward: Why we need YOU to give blood, National plan for the management of shortages of labile blood components, Phenotype matching for sickle cell patients: A review and recommendations for transfusion practice, Transfusion-related acute lung injury (TRALI), Emergency framework for rationing of blood for massively bleeding patients during a red phase blood shortage, Platelet product quality remains high after seven days of storage, A survey of Canadian MLTs’ views on continuing education in transfusion science, Alternative methods of blood donor skin disinfection, Exploring the frontiers of IVIG-associated hemolysis, Striking the balance: protecting data privacy in research, The importance of iron for whole blood donors: a Canadian perspective, Canadian Society for Transfusion Medicine (CSTM), National Advisory Committee on Blood and Blood Products, https://choosingwiselycanada.org/transfusion-medicine/, http://www.nacblood.ca/resources/guidelines/CMV.html. Plasma pooled from many donors, treated with processing steps (solvent detergent, immune neutralisation, sterile filtration) to remove or inactivate pathogens, cells, allergens and antibodies. Figure 1 highlights the main steps of both manufacturing processes.
Transfusion Medicine Recommendations, Choosing Wisely Canada2015. For Apheresis Gambro Trima collection packs the minimum volume is 100 ml. Aliquots obtained using such a device retain the seven day expiry date and must contain a minimum residual volume that is dependent on the collection pack.
AFFP or FP is usually used in these situations when CSP is not available. Options for sealing include heat seal, clamping, or if these are not available, placement of a tight slip knot in the tubing, (i.e., tighten until the tubing in the knot is a white color).